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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4781e220d7c0d8a36123add9795c2d4a2efe0fc8f1fa5e456a039c87b9b2e3df' 
  AND token = 'gW1QRgU7TcRfQhNifKaHa5Af62OOY88ShaH2AyEJ7kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}