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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d330a9a7bb49bcb8f5e562b63e1bc0e1db147d26347bf75ac94728a60f6136a' 
  AND token = 'Mtk7rB5WBT1oYeCig6/7M5WEP9oe9o70ehlw15S3wYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}