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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ea0a7a5221e7b0eae22386d2e0d9f46bc2ed4cf67a1171ac9650bd1484d813' 
  AND token = '0QE4dMEZmIWJB3tEPtQ1aE9q4djOLKdpO28k+/O9isY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}