SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a672e8cc32253ee73d6de62e13a81b7b1cbac360063ab07c8ee1b37a758f12' 
  AND token = 'hTYtgRJTMz1zcQ8MF8aJZNT2hG7aMSyiDRqQdS7R4qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}