SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e51eabfd8bda812af079be8e8236336b5536530dde008e7ab480b00b6fed06' 
  AND token = 'l4M6GOODk95vXqF3Ib0UZtAnIRGKYNst5XS771Jpn1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}