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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d498cf764fae3e94078a61010b95b5a580f69055216d8d2cbac708d4ef3c43' 
  AND token = 'ACp6tCwFmoZq5f1zZBfkY3Lpo14BtNfaX0oz2knQO2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}