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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aa189405f4f8df1f222204d9916cf044fa197a5d2c924299f35e9056aa4197b' 
  AND token = 'iV19aD5XJGlUjMZdYFawgVr5q+aUWmIQY3SgmtjC05k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}