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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74197490f867d9f404e9aa2b8364eeeb8522ef396aee6bdbc8b8855477237f52' 
  AND token = '3RQnkW2BJnLVvCDuvD5jMEk41W4FMJQJa73XYOGYf0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}