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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7236ed143276acbb3bbc84cb58b035b25035017ca250847765252f32001781c7' 
  AND token = 'RM2/MvvHGGO4uz9hMpaPFFt91llcbY2nEemEAIktw+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}