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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d7db86774fbec606381976e5596cd208ad9f9cd55ed97b8510bf14dcf82250' 
  AND token = 'iGG30U6PcEUMV9sRMzMl7IqQ2nh8H90mWVw7d0u92DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}