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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72379626249fd891fbe6d287423ab587f08b09afebeabb0a3e65db003758db6a' 
  AND token = 'uJSlod+YbphBflJPpOXiMwSh+paO8cY7I013IE4QRs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}