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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b2fe7e6a17b675c591540b170088b411060a4df9ff301e1dc633da7f80fa5a' 
  AND token = 'w3VQnxpQU3Vr/97tyJzAk7+bjKtAvIr6odZ1sP0BpFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}