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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed82588010c62d0264264b261c2f456e730982c490000edf7c9e36292f49077' 
  AND token = 'OX3Mt0kUqWm9vB9NrKnVmbjFRn0GDWwnRZUDKYtDJtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}