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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb5af5a42de2525aa95bc9170286e49fc488005df3c4f2e0cfe504f51aabb294' 
  AND token = 'kiShny66PfrcW+2uB20KhrB3Yv30CYb9Reywuj6ntOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}