SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204550730c01d36fcf351af9250ef424c12a1c2545d12af602dd8672cba56d29' 
  AND token = '+Wmo5sKFxNmU6EwoQBydllszxgFeKxMoFi+0aD8khrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}