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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19fe0cd2db3be3827c915740d8cbb1cf2397189f42d5beae80703928f933b457' 
  AND token = 'Z8I4Xj/gnBUxRMkwL4Wqi3FsMcQVTGeoDB5EmrfmJfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}