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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '438f494b62d0377ef3b5084cb2a6f1dd87d1f9ee21bd902f59b7ecc6bd79d89a' 
  AND token = 'Z6cvMBmeYcWYNpE+TTmIo5v1AUmxBEfnOE0HU9dU/zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}