SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13f23352c475dff10858e05a7cfabeaca5970713afc4293b455757c83e5927dc' 
  AND token = 'NbM/GfvyTK+U+uS605tbmWU4xQiOHAUuZVwUHqoapT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}