SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc7e6049dc56f896c49b51f44f4f771f01a066b91e73bc17e5aa1c0d2ca6a683' 
  AND token = 'USFmZhrzaPlErLNiIdE9akOfa7zfHu7egW0NLWMmF5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}