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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b0f003d49d137373efc9b8d379a9d4080d94d393bc334d18124e2ae122959f' 
  AND token = '0E7THY5dYa+bjAaTcXzZUeSfHyP+e+jg/7BOC7/FaGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}