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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ef8322602c889ca20406d1ec869657c055fc99dce563f2d9c213c26d32be00' 
  AND token = 'dFHKxySgOhpOX9qBDc7bWhbCkPzV+GG10nFdqE+h7Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}