SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae16116914953f8e2bae88df2a34e9d20382a2b9992e4720784387b2f115d0b' 
  AND token = 'XZw+2SAUv0yYWa521I2caGB9WPUz98lEn5mwsWtCJRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}