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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e44de235e1e6992bd27d51a67dae48f6c868c899e732f135484f53f05a2fd03' 
  AND token = 'ROZdiHFFV+Ou4GCWkmdJREblJevIqHaIfmoI2ofKYX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}