SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ecc43fcc31d99457ed45a402137d1ceffd35d4c2baf550685b66ad58c26d3c1' 
  AND token = 'Eq/zXSKhXcT9xs/aJRX8TTT8sPbDUGXYh//8ekVpBAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}