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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecf460897822818b0f4454ffe7937ce16a432218d956d7ee227f53e673f3993' 
  AND token = 'r1cZJ7yc8xeW5lZshhOpgqQlalJHsXvyyaWRoXP/GQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}