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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604bc4947c56a3ab40330d79a0202759cd8d92e38e4f721fd6d256e7d0070530' 
  AND token = 'BKfr4VT8MYEtKa8tEM4BB74nlYyy+Sw4LWkxda6hKSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}