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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d182e5350203e32b8cfe0497cb20d7d70b74f2a81088e5adfde7e14822f707' 
  AND token = '9ZBd0NoaFutIPPYgB7jNyLTZpU4LWknqwXcPKk+CAdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}