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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149077425fa74c5517158b69f5874e89c47fbd2ac2a7e60b9077e0de2a31f537' 
  AND token = 'L9rdnd5eI5IsiGUMrJHZj1zdZcXncIuQp7cPj7cU/SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}