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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1572f56b141bd7ed1b85f185531b56f7797570eae292f77702aaa8aa363288b4' 
  AND token = '8aAg+FwbThk5EZ8+UV5EScrWGgN8UzStsMPmZN2ZTNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}