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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721a8157c0977b0e6b924dfa54b720f2655eb703a9ccbc21eec68b250621c4ff' 
  AND token = 'OmoSmSaqv14FZsN9PxV77MGT8E6vSqS0mRl1RVxrN+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}