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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c36fa35992452c9d505aa8e255fe4251ed5d444206932211a1cd25927a38dfd' 
  AND token = 'sViZub4hxzLsB1TTw+ES/LISUuOrgRAZ2sQ/Wp27BpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}