SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db2226b7c90c73e6abecc4842f9abcc8cee9d6e1b1f73e2bec02a2df1e742d1d' 
  AND token = 'c7mnsV564GR7e9IZbetSuRhrj4TXORuSC2SHYazG8Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}