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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a1caa32e0290ebbc70ab5df23dd190fff5c24e74141f6cad0cadf046139312' 
  AND token = 'ZZjYVZ1LWfDyp4CHuWKfCM6Gw5qePDUD47c7Rd0NBr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}