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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f1c5b1fb77edc59c8fcb6a84065bf18da9cf7e8ffba0231166eb0fa77591ac2' 
  AND token = 'B1Gj7eTK1ZNeBmzyo2ntr8qC6oWvFM/s/CPe0h0KNkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}