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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6edfea718e4620011ad16464b29f47ae19530dbca674bc31ea38f7a2feb2e8b7' 
  AND token = 'vOWI2E6P7pnrdf2V/neA0ihZPhmTyWFfv6HZmPH+PY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}