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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '445a326f2a1e11e5ba37ffc0afed6e2cc6aae3510c9f65ee52e809e3608a717c' 
  AND token = 'J15G7uTyNUBN/TZSAbfPJZAetPJIJ9C86C3RGgCOzkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}