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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f126a74d130004755594fdbcd95a816fd2a157785b405be48f46d4a0b17e04' 
  AND token = 'YJQDHLJiJfzqjyIJoaWO1kk5ziLzEEaozVHuD6TdZ5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}