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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b305b09b6ba5e1d76e2f096d4737f77b78bd8f46d554cbe905a86af451ba1022' 
  AND token = 'ipBwH6ZiJC2iQfMQ/mpguldg8X+iaUelkADFTqTPDWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}