SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e3d01a18b2a2d1b71abc86ca3bf37fe971cf8f24c41a72aa4b36da1bf0a495' 
  AND token = 'tx2l2jgJXylQIrcev61jKSq3SsgZEWH6ZWMeDZyWfQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}