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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb351ce130058500e34bf1658f7d9370b244626c821607f1c5b7fca2f4cb41a' 
  AND token = '7Bj+NgrwB5YnEHmQxBGTcyQ7zZpusPiOlTTW17yKHR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}