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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3cf5f3c66128cb65228554eb47b77053aed3efa4b2aff548e94e663a1dd3d1' 
  AND token = 'F1At4wRI3/UjfWhhX6dG9rf7Is3i3EmiRdIUAtSQVWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}