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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185f36794873d01650c53be882efcf6a698bc9c150248089be6902f28c5f4bc1' 
  AND token = 'tdKUW71919ele+T0sSohKYX31003XnS+5aR6c3tPDLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}