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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af765463f70682cdb5862f056770b18b04ea2e7e3c11880c8fe5264d016620af' 
  AND token = 'qiM0angDFatQMtd+g/3mjCecxXz8MQ1KbOzElLSJS3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}