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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0b5b5aaaffa0fc65b910ea63830aa871488e7fd352ebc06304ea6b744fbb2e' 
  AND token = 'mLSiub7RnhJkcu1P1BUlOJRYzdS7nSGeIxSHdLDd9kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}