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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b9614a07402a65ab257882ed79afa0e00c9f158eaeb2c6d652e0d0c6560d109' 
  AND token = '7+Km6wz1xUIwzUPAzP3Q6S/Hm0yBYL7Rl/5kWgpTC50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}