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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78f13536853ef327ec73c46403919a93fb6c3e987a4f69ffd28eb0d9af6a4cd' 
  AND token = '3eSxZEANjFHmCz7rQc9vzF0zp+bhArZ/B8nmhRmNodk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}