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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b957fd35157a540cb8cc983590a9a28eb82bb92744aea1c1b58c72148591ec' 
  AND token = 'dldZA4VFdoKQycwZ5NqR7uyMiOC0KyBGW9TWEn6HYMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}