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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9972bec7cb21746b9dc1d492a63f98f9dcc08c8d19f8147b5052dd0e061886' 
  AND token = '6tB/XrjJ5LoRWVCbmb9XNpzI3ECoPiqM+AbiVy4lgzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}