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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06c3bf7bdf887719d530d569ba851430e7ac437f7bc89377a384d5e52defb8fe' 
  AND token = 'v9EXW8E0OXSAFESZ6fUg701PpvRUQ6UNgEd0gcxt4PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}