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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77374340da0868569c7d9af993d651f158a14f7bd43972909c9c59f253435c73' 
  AND token = 'Y+uFfZee0QxbLsaJYYfQOSZ0mlEkn2W0CIxBcEKEj+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}